DONEPEZIL

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	RACEMIC
Molecular Formula	C24H29NO3
Molecular Weight	379.492
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of DONEPEZIL

Structure Search

SMILES

COC1=CC2=C(C=C1OC)C(=O)C(CC3CCN(CC4=CC=CC=C4)CC3)C2

InChI

InChIKey=ADEBPBSSDYVVLD-UHFFFAOYSA-N

InChI=1S/C24H29NO3/c1-27-22-14-19-13-20(24(26)21(19)15-23(22)28-2)12-17-8-10-25(11-9-17)16-18-6-4-3-5-7-18/h3-7,14-15,17,20H,8-13,16H2,1-2H3

HIDE SMILES / InChI

Molecular Formula	C24H29NO3
Molecular Weight	379.492
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:15:49 UTC 2023` Edited by `admin` on `Fri Dec 15 16:15:49 UTC 2023`
Record UNII	8SSC91326P
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

DONEPEZIL

Official Name

English

D-797

Common Name

English

1-BENZYL-4-((5,6-DIMETHOXY-1-INDANON-2-YL)METHYL)PIPERIDINE

Systematic Name

English

DONAZ

Brand Name

English

5,6-DIMETHOXY-2-((1-(PHENYLMETHYL)-4-PIPERIDINYL)METHYL)-2,3-DIHYDRO-1H-INDEN-1-ONE

Systematic Name

English

Donepezil [WHO-DD]

Common Name

English

DONEPEZIL [JAN]

Common Name

English

donepezil [INN]

Common Name

English

(±)-2-((1-BENZYL-4-PIPERIDYL)METHYL)-5,6-DIMETHOXY-1-INDANONE

Systematic Name

English

1H-INDEN-1-ONE, 2,3-DIHYDRO-5,6-DIMETHOXY-2-((1-(PHENYLMETHYL)-4-PIPERIDINYL)METHYL)-

Systematic Name

English

DONEPEZIL [HSDB]

Common Name

English

DONEPEZIL [VANDF]

Common Name

English

2,3-DIHYDRO-5,6-DIMETHOXY-2-((1-(PHENYLMETHYL)-4-PIPERIDINYL)METHYL)-1H-INDEN-1-ONE

Systematic Name

English

D797

Common Name

English

DONEPEZIL [MI]

Common Name

English

Classification Tree Code System Code

NDF-RT

N0000175723

Created by admin on Fri Dec 15 16:15:49 UTC 2023 , Edited by admin on Fri Dec 15 16:15:49 UTC 2023

WHO-VATC

QN06DA02

Created by admin on Fri Dec 15 16:15:49 UTC 2023 , Edited by admin on Fri Dec 15 16:15:49 UTC 2023

NDF-RT

N0000000177

Created by admin on Fri Dec 15 16:15:49 UTC 2023 , Edited by admin on Fri Dec 15 16:15:49 UTC 2023

WHO-VATC

QN06DA52

Created by admin on Fri Dec 15 16:15:49 UTC 2023 , Edited by admin on Fri Dec 15 16:15:49 UTC 2023

WHO-ATC

N06DA52

Created by admin on Fri Dec 15 16:15:49 UTC 2023 , Edited by admin on Fri Dec 15 16:15:49 UTC 2023

LIVERTOX

NBK548197

Created by admin on Fri Dec 15 16:15:49 UTC 2023 , Edited by admin on Fri Dec 15 16:15:49 UTC 2023

WHO-ATC

N06DA53

Created by admin on Fri Dec 15 16:15:49 UTC 2023 , Edited by admin on Fri Dec 15 16:15:49 UTC 2023

WHO-ATC

N06DA02

Created by admin on Fri Dec 15 16:15:49 UTC 2023 , Edited by admin on Fri Dec 15 16:15:49 UTC 2023

NCI_THESAURUS

C47792

Created by admin on Fri Dec 15 16:15:49 UTC 2023 , Edited by admin on Fri Dec 15 16:15:49 UTC 2023

Code System Code Type Description

RXCUI

135447

Created by admin on Fri Dec 15 16:15:49 UTC 2023 , Edited by admin on Fri Dec 15 16:15:49 UTC 2023

PRIMARY

RxNorm

CAS

120014-06-4

Created by admin on Fri Dec 15 16:15:49 UTC 2023 , Edited by admin on Fri Dec 15 16:15:49 UTC 2023

PRIMARY

FDA UNII

8SSC91326P

Created by admin on Fri Dec 15 16:15:49 UTC 2023 , Edited by admin on Fri Dec 15 16:15:49 UTC 2023

PRIMARY

DAILYMED

8SSC91326P

Created by admin on Fri Dec 15 16:15:49 UTC 2023 , Edited by admin on Fri Dec 15 16:15:49 UTC 2023

PRIMARY

WIKIPEDIA

DONEPEZIL

Created by admin on Fri Dec 15 16:15:49 UTC 2023 , Edited by admin on Fri Dec 15 16:15:49 UTC 2023

PRIMARY

CHEBI

53289

Created by admin on Fri Dec 15 16:15:49 UTC 2023 , Edited by admin on Fri Dec 15 16:15:49 UTC 2023

PRIMARY

MESH

C076946

Created by admin on Fri Dec 15 16:15:49 UTC 2023 , Edited by admin on Fri Dec 15 16:15:49 UTC 2023

PRIMARY

MERCK INDEX

m4738

Created by admin on Fri Dec 15 16:15:49 UTC 2023 , Edited by admin on Fri Dec 15 16:15:49 UTC 2023

PRIMARY

Merck Index

INN

7517

Created by admin on Fri Dec 15 16:15:49 UTC 2023 , Edited by admin on Fri Dec 15 16:15:49 UTC 2023

PRIMARY

DRUG CENTRAL

946

Created by admin on Fri Dec 15 16:15:49 UTC 2023 , Edited by admin on Fri Dec 15 16:15:49 UTC 2023

PRIMARY

SMS_ID

100000080761

Created by admin on Fri Dec 15 16:15:49 UTC 2023 , Edited by admin on Fri Dec 15 16:15:49 UTC 2023

PRIMARY

DRUG BANK

DB00843

Created by admin on Fri Dec 15 16:15:49 UTC 2023 , Edited by admin on Fri Dec 15 16:15:49 UTC 2023

PRIMARY

IUPHAR

6599

Created by admin on Fri Dec 15 16:15:49 UTC 2023 , Edited by admin on Fri Dec 15 16:15:49 UTC 2023

PRIMARY

HSDB

7743

Created by admin on Fri Dec 15 16:15:49 UTC 2023 , Edited by admin on Fri Dec 15 16:15:49 UTC 2023

PRIMARY

ChEMBL

CHEMBL502

Created by admin on Fri Dec 15 16:15:49 UTC 2023 , Edited by admin on Fri Dec 15 16:15:49 UTC 2023

PRIMARY

EVMPD

SUB06362MIG

Created by admin on Fri Dec 15 16:15:49 UTC 2023 , Edited by admin on Fri Dec 15 16:15:49 UTC 2023

PRIMARY

NCI_THESAURUS

C66874

Created by admin on Fri Dec 15 16:15:49 UTC 2023 , Edited by admin on Fri Dec 15 16:15:49 UTC 2023

PRIMARY

EPA CompTox

DTXSID8048317

Created by admin on Fri Dec 15 16:15:49 UTC 2023 , Edited by admin on Fri Dec 15 16:15:49 UTC 2023

PRIMARY

PUBCHEM

3152

Created by admin on Fri Dec 15 16:15:49 UTC 2023 , Edited by admin on Fri Dec 15 16:15:49 UTC 2023

PRIMARY

Related Record Type Details


					3O2T2PJ89D

DONEPEZIL HYDROCHLORIDE

SALT/SOLVATE -> PARENT


					8E4LAA4357

CYTOCHROME P450 2D6

METABOLIC ENZYME -> SUBSTRATE


					SLF7M28SI5

DONEPEZIL OXALATE

SALT/SOLVATE -> PARENT


					EK71H4HC3N

ACETYLCHOLINESTERASE HUMAN

TARGET -> INHIBITOR

Amount:

Related Record Type Details


					X070Q7TQO8

DONEPEZIL N-OXIDE

METABOLITE -> PARENT


					97R9M0LYM7

5-O-DESMETHYLDONEPEZIL GLUCURONIDE

METABOLITE -> PARENT


					C870X5D93I

DONEPEZIL N-OXIDE, TRANS-

METABOLITE -> PARENT


					56R452SD5N

5-O-DESMETHYL DONEPEZIL

METABOLITE -> PARENT


					1O435436YC

6-O-DESMETHYLDONEPEZIL GLUCURONIDE

METABOLITE -> PARENT


					556XXE4I5F

6-O-DESMETHYLDONEPEZIL

METABOLITE -> PARENT


					D84X9FAD1Y

DESBENZYL DONEPEZIL

METABOLITE -> PARENT


					E928P2KJ7Y

DONEPEZIL N-OXIDE, CIS-

METABOLITE -> PARENT

Related Record Type Details


					2YE6CPY2J4

3-HYDROXYDONEPEZIL

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

USP

Amount:


					AGY4FP2TTK

DONEPEZIL OPEN-RING KETO ACID

IMPURITY -> PARENT

Amount:

Related Record Type Details


					8SSC91326P

DONEPEZIL

ACTIVE MOIETY