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Details

Stereochemistry ABSOLUTE
Molecular Formula C22H29FO5
Molecular Weight 392.4611
Optical Activity UNSPECIFIED
Defined Stereocenters 8 / 8
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of BETAMETHASONE

SMILES

[H][C@@]12C[C@H](C)[C@](O)(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]3(F)[C@@]2([H])CCC4=CC(=O)C=C[C@]34C

InChI

InChIKey=UREBDLICKHMUKA-DVTGEIKXSA-N
InChI=1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15-,16-,17-,19-,20-,21-,22-/m0/s1

HIDE SMILES / InChI
Molecular Formula C22H29FO5
Molecular Weight 392.4611
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 8 / 8
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

Unknown
86413
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:12:58 UTC 2023
Edited
by admin
on Fri Dec 15 15:12:58 UTC 2023
Record UNII
9842X06Q6M
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
BETAMETHASONE
EP   HSDB   INN   MART.   MI   ORANGE BOOK   USAN   USP   USP-RS   VANDF   WHO-DD   WHO-IP  
INN   USAN  
Official Name English
VISUBETA
Code English
FLOSTERON
Common Name English
BETAMETHASONE [VANDF]
Common Name English
FLUBENISOLONE
Common Name English
BETAMETHASONE [JAN]
Common Name English
SCH-4831
Code English
BETAMETHASONE DIPROPIONATE IMPURITY A
Common Name English
RINDERON
Brand Name English
BETAMETHASONUM [WHO-IP LATIN]
Common Name English
SCH 4831
Code English
BETAMETHASONE VALERATE IMPURITY A [EP IMPURITY]
Common Name English
BETAMETHASONE [WHO-IP]
Common Name English
BETAMETHASONE [MART.]
Common Name English
CELESTONE
Brand Name English
BETAMETHASONE [MI]
Common Name English
BETAMETHASONE [USP-RS]
Common Name English
BETAMETHASONE [USAN]
Common Name English
NSC-39470
Code English
DESACORT-BETA
Common Name English
betamethasone [INN]
Common Name English
CELESTENE
Common Name English
PREGNA-1,4-DIENE-3,20-DIONE, 9-FLUORO-11,17,21-TRIHYDROXY-16-METHYL-, (11.BETA.,16.BETA.)-
Systematic Name English
BETAMETHASONE ACETATE IMPURITY A [EP IMPURITY]
Common Name English
Betamethasone [WHO-DD]
Common Name English
BETAMETHASONE [EP IMPURITY]
Common Name English
DEXAMETHASONE IMPURITY B [EP IMPURITY]
Common Name English
9-FLUORO-11.BETA.,17,21-TRIHYDROXY-16.BETA.-METHYLPREGNA-1,4-DIENE-3,20-DIONE.
Systematic Name English
BETAMETHASONE [USP MONOGRAPH]
Common Name English
BETAMETHASONE [EP MONOGRAPH]
Common Name English
BETAMETHASONE [ORANGE BOOK]
Common Name English
Classification Tree Code System Code
WHO-VATC QS03BA03
Created by admin on Fri Dec 15 15:12:59 UTC 2023 , Edited by admin on Fri Dec 15 15:12:59 UTC 2023
CFR 21 CFR 524.1044D
Created by admin on Fri Dec 15 15:12:58 UTC 2023 , Edited by admin on Fri Dec 15 15:12:58 UTC 2023
CFR 21 CFR 524.1044I
Created by admin on Fri Dec 15 15:12:58 UTC 2023 , Edited by admin on Fri Dec 15 15:12:58 UTC 2023
WHO-ATC R03BA04
Created by admin on Fri Dec 15 15:12:58 UTC 2023 , Edited by admin on Fri Dec 15 15:12:58 UTC 2023
CFR 21 CFR 524.1044B
Created by admin on Fri Dec 15 15:12:58 UTC 2023 , Edited by admin on Fri Dec 15 15:12:58 UTC 2023
WHO-VATC QA07EA04
Created by admin on Fri Dec 15 15:12:59 UTC 2023 , Edited by admin on Fri Dec 15 15:12:59 UTC 2023
WHO-ATC D07AC01
Created by admin on Fri Dec 15 15:12:58 UTC 2023 , Edited by admin on Fri Dec 15 15:12:58 UTC 2023
FDA ORPHAN DRUG 492415
Created by admin on Fri Dec 15 15:12:59 UTC 2023 , Edited by admin on Fri Dec 15 15:12:59 UTC 2023
NDF-RT N0000175576
Created by admin on Fri Dec 15 15:12:59 UTC 2023 , Edited by admin on Fri Dec 15 15:12:59 UTC 2023
WHO-VATC QD07BC01
Created by admin on Fri Dec 15 15:12:59 UTC 2023 , Edited by admin on Fri Dec 15 15:12:59 UTC 2023
WHO-ATC D07CC01
Created by admin on Fri Dec 15 15:12:58 UTC 2023 , Edited by admin on Fri Dec 15 15:12:58 UTC 2023
WHO-ATC S01BB04
Created by admin on Fri Dec 15 15:12:58 UTC 2023 , Edited by admin on Fri Dec 15 15:12:58 UTC 2023
WHO-VATC QD07CC01
Created by admin on Fri Dec 15 15:12:59 UTC 2023 , Edited by admin on Fri Dec 15 15:12:59 UTC 2023
NDF-RT N0000175450
Created by admin on Fri Dec 15 15:12:59 UTC 2023 , Edited by admin on Fri Dec 15 15:12:59 UTC 2023
WHO-VATC QR03BA04
Created by admin on Fri Dec 15 15:12:59 UTC 2023 , Edited by admin on Fri Dec 15 15:12:59 UTC 2023
WHO-ATC S01CA05
Created by admin on Fri Dec 15 15:12:58 UTC 2023 , Edited by admin on Fri Dec 15 15:12:58 UTC 2023
WHO-VATC QS02CA90
Created by admin on Fri Dec 15 15:12:59 UTC 2023 , Edited by admin on Fri Dec 15 15:12:59 UTC 2023
WHO-ATC S01CB04
Created by admin on Fri Dec 15 15:12:58 UTC 2023 , Edited by admin on Fri Dec 15 15:12:58 UTC 2023
WHO-ATC A07EA04
Created by admin on Fri Dec 15 15:12:58 UTC 2023 , Edited by admin on Fri Dec 15 15:12:58 UTC 2023
WHO-ESSENTIAL MEDICINES LIST 13.3
Created by admin on Fri Dec 15 15:12:59 UTC 2023 , Edited by admin on Fri Dec 15 15:12:59 UTC 2023
WHO-VATC QS01BA06
Created by admin on Fri Dec 15 15:12:59 UTC 2023 , Edited by admin on Fri Dec 15 15:12:59 UTC 2023
WHO-ATC H02AB01
Created by admin on Fri Dec 15 15:12:58 UTC 2023 , Edited by admin on Fri Dec 15 15:12:58 UTC 2023
WHO-ATC S01BA06
Created by admin on Fri Dec 15 15:12:58 UTC 2023 , Edited by admin on Fri Dec 15 15:12:58 UTC 2023
CFR 21 CFR 524.1044G
Created by admin on Fri Dec 15 15:12:58 UTC 2023 , Edited by admin on Fri Dec 15 15:12:58 UTC 2023
WHO-VATC QD07XC01
Created by admin on Fri Dec 15 15:12:59 UTC 2023 , Edited by admin on Fri Dec 15 15:12:59 UTC 2023
WHO-VATC QS01CB04
Created by admin on Fri Dec 15 15:12:59 UTC 2023 , Edited by admin on Fri Dec 15 15:12:59 UTC 2023
WHO-VATC QH02AB01
Created by admin on Fri Dec 15 15:12:59 UTC 2023 , Edited by admin on Fri Dec 15 15:12:59 UTC 2023
CFR 21 CFR 524.1044F
Created by admin on Fri Dec 15 15:12:58 UTC 2023 , Edited by admin on Fri Dec 15 15:12:58 UTC 2023
WHO-ATC R01AD06
Created by admin on Fri Dec 15 15:12:58 UTC 2023 , Edited by admin on Fri Dec 15 15:12:58 UTC 2023
WHO-ATC D07XC01
Created by admin on Fri Dec 15 15:12:58 UTC 2023 , Edited by admin on Fri Dec 15 15:12:58 UTC 2023
WHO-VATC QC05AA05
Created by admin on Fri Dec 15 15:12:59 UTC 2023 , Edited by admin on Fri Dec 15 15:12:59 UTC 2023
NCI_THESAURUS C521
Created by admin on Fri Dec 15 15:12:59 UTC 2023 , Edited by admin on Fri Dec 15 15:12:59 UTC 2023
WHO-ATC S02BA07
Created by admin on Fri Dec 15 15:12:58 UTC 2023 , Edited by admin on Fri Dec 15 15:12:58 UTC 2023
WHO-VATC QS03CA06
Created by admin on Fri Dec 15 15:12:59 UTC 2023 , Edited by admin on Fri Dec 15 15:12:59 UTC 2023
WHO-ATC D07BC01
Created by admin on Fri Dec 15 15:12:58 UTC 2023 , Edited by admin on Fri Dec 15 15:12:58 UTC 2023
LIVERTOX 100
Created by admin on Fri Dec 15 15:12:59 UTC 2023 , Edited by admin on Fri Dec 15 15:12:59 UTC 2023
WHO-VATC QS01BB04
Created by admin on Fri Dec 15 15:12:59 UTC 2023 , Edited by admin on Fri Dec 15 15:12:59 UTC 2023
WHO-ATC S03CA06
Created by admin on Fri Dec 15 15:12:58 UTC 2023 , Edited by admin on Fri Dec 15 15:12:58 UTC 2023
WHO-ATC S03BA03
Created by admin on Fri Dec 15 15:12:58 UTC 2023 , Edited by admin on Fri Dec 15 15:12:58 UTC 2023
WHO-VATC QD07AC01
Created by admin on Fri Dec 15 15:12:59 UTC 2023 , Edited by admin on Fri Dec 15 15:12:59 UTC 2023
WHO-VATC QS01CA05
Created by admin on Fri Dec 15 15:12:59 UTC 2023 , Edited by admin on Fri Dec 15 15:12:59 UTC 2023
WHO-ATC C05AA05
Created by admin on Fri Dec 15 15:12:58 UTC 2023 , Edited by admin on Fri Dec 15 15:12:58 UTC 2023
WHO-VATC QR01AD06
Created by admin on Fri Dec 15 15:12:59 UTC 2023 , Edited by admin on Fri Dec 15 15:12:59 UTC 2023
WHO-VATC QS02BA07
Created by admin on Fri Dec 15 15:12:59 UTC 2023 , Edited by admin on Fri Dec 15 15:12:59 UTC 2023
Code System Code Type Description
RXCUI
1514
Created by admin on Fri Dec 15 15:12:59 UTC 2023 , Edited by admin on Fri Dec 15 15:12:59 UTC 2023
PRIMARY RxNorm
CHEBI
3077
Created by admin on Fri Dec 15 15:12:58 UTC 2023 , Edited by admin on Fri Dec 15 15:12:58 UTC 2023
PRIMARY
MERCK INDEX
m2452
Created by admin on Fri Dec 15 15:12:59 UTC 2023 , Edited by admin on Fri Dec 15 15:12:59 UTC 2023
PRIMARY Merck Index
MESH
D001623
Created by admin on Fri Dec 15 15:12:59 UTC 2023 , Edited by admin on Fri Dec 15 15:12:59 UTC 2023
PRIMARY
LACTMED
Betamethasone
Created by admin on Fri Dec 15 15:12:59 UTC 2023 , Edited by admin on Fri Dec 15 15:12:59 UTC 2023
PRIMARY
ChEMBL
CHEMBL632
Created by admin on Fri Dec 15 15:12:58 UTC 2023 , Edited by admin on Fri Dec 15 15:12:58 UTC 2023
PRIMARY
EVMPD
SUB05797MIG
Created by admin on Fri Dec 15 15:12:58 UTC 2023 , Edited by admin on Fri Dec 15 15:12:58 UTC 2023
PRIMARY
NCI_THESAURUS
C303
Created by admin on Fri Dec 15 15:12:59 UTC 2023 , Edited by admin on Fri Dec 15 15:12:59 UTC 2023
PRIMARY
SMS_ID
100000091947
Created by admin on Fri Dec 15 15:12:59 UTC 2023 , Edited by admin on Fri Dec 15 15:12:59 UTC 2023
PRIMARY
WHO INTERNATIONAL PHARMACOPEIA
BETAMETHASONE
Created by admin on Fri Dec 15 15:12:59 UTC 2023 , Edited by admin on Fri Dec 15 15:12:59 UTC 2023
PRIMARY Description: A white or creamy white powder; odourless. Solubility: Practically insoluble in water; sparingly soluble in ethanol (~750 g/l) TS. Category: Adrenoglucocorticoid. Storage: Betamethasone should be kept in a tightly closed container, protected from light. Definition: Betamethasone contains not less than 96.0% and not more than 104.0% of C22H29FO5 calculated with reference to the dried substance.
WIKIPEDIA
BETAMETHASONE
Created by admin on Fri Dec 15 15:12:59 UTC 2023 , Edited by admin on Fri Dec 15 15:12:59 UTC 2023
PRIMARY
EPA CompTox
DTXSID3022667
Created by admin on Fri Dec 15 15:12:59 UTC 2023 , Edited by admin on Fri Dec 15 15:12:59 UTC 2023
PRIMARY
HSDB
3015
Created by admin on Fri Dec 15 15:12:59 UTC 2023 , Edited by admin on Fri Dec 15 15:12:59 UTC 2023
PRIMARY
PUBCHEM
9782
Created by admin on Fri Dec 15 15:12:59 UTC 2023 , Edited by admin on Fri Dec 15 15:12:59 UTC 2023
PRIMARY
INN
1045
Created by admin on Fri Dec 15 15:12:59 UTC 2023 , Edited by admin on Fri Dec 15 15:12:59 UTC 2023
PRIMARY
LACTMED
Betamethasone, Topical
Created by admin on Fri Dec 15 15:12:59 UTC 2023 , Edited by admin on Fri Dec 15 15:12:59 UTC 2023
PRIMARY
CAS
378-44-9
Created by admin on Fri Dec 15 15:12:58 UTC 2023 , Edited by admin on Fri Dec 15 15:12:58 UTC 2023
PRIMARY
FDA UNII
9842X06Q6M
Created by admin on Fri Dec 15 15:12:59 UTC 2023 , Edited by admin on Fri Dec 15 15:12:59 UTC 2023
PRIMARY
RS_ITEM_NUM
1066009
Created by admin on Fri Dec 15 15:12:59 UTC 2023 , Edited by admin on Fri Dec 15 15:12:59 UTC 2023
PRIMARY
DAILYMED
9842X06Q6M
Created by admin on Fri Dec 15 15:12:58 UTC 2023 , Edited by admin on Fri Dec 15 15:12:58 UTC 2023
PRIMARY
NSC
39470
Created by admin on Fri Dec 15 15:12:59 UTC 2023 , Edited by admin on Fri Dec 15 15:12:59 UTC 2023
PRIMARY
DRUG BANK
DB00443
Created by admin on Fri Dec 15 15:12:59 UTC 2023 , Edited by admin on Fri Dec 15 15:12:59 UTC 2023
PRIMARY
ECHA (EC/EINECS)
206-825-4
Created by admin on Fri Dec 15 15:12:59 UTC 2023 , Edited by admin on Fri Dec 15 15:12:59 UTC 2023
PRIMARY
DRUG CENTRAL
348
Created by admin on Fri Dec 15 15:12:59 UTC 2023 , Edited by admin on Fri Dec 15 15:12:59 UTC 2023
PRIMARY
IUPHAR
7061
Created by admin on Fri Dec 15 15:12:59 UTC 2023 , Edited by admin on Fri Dec 15 15:12:59 UTC 2023
PRIMARY
Related Record Type Details
Structure of BETAMETHASONE-.DELTA.17,20 21-ALDEHYDE
DEGRADENT -> PARENT
When catalyzed by sulfuric acid only.
Structure of 16.DELTA.-BETAMETHASONE
DEGRADENT -> PARENT
Structure of BETAMETHASONE
BASIS OF STRENGTH->SUBSTANCE
ASSAY (UV)
EP
Structure of BETAMETHASONE SODIUM
SALT/SOLVATE -> PARENT
PLASMA PROTEIN FRACTION (HUMAN)
BINDER->LIGAND
BINDING
Related Record Type Details
Structure of BETAMETHASONE 21-(ETHYL CARBONATE)
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of CLOBETASOL
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of BETAMETHASONE ACETATE
PARENT -> IMPURITY
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of DEXAMETHASONE
PARENT -> IMPURITY
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of BETAMETHASONE VALERATE
PARENT -> IMPURITY
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of 17,21-DIHYDROXY-16.BETA.-METHYLPREGNA-1,4-DIENE-3,20-DIONE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of 17,21-DIHYDROXY-16.BETA.-METHYLPREGNA-1,4,9(11)-TRIENE-3,20-DIONE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of 17,21-DIHYDROXY-16.BETA.-METHYLPREGNA-1,4,11-TRIENE-3,20-DIONE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of 14-FLUORO-11.BETA.,17,21-TRIHYDROXY-16.BETA.-METHYL-8.ALPHA.,9.BETA.,14.BETA.-PREGNA-1,4-DIENE-3,20-DIONE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of BETAMETHASONE 9,11-EPOXIDE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of 8-FLUORO-11.BETA.,17,21-TRIHYDROXY-16.BETA.-METHYL-8.ALPHA.,9.BETA.-PREGNA-1,4-DIENE-3,20-DIONE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of DEXAMETHASONE
PARENT -> IMPURITY
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of BETAMETHASONE DIPROPIONATE
PARENT -> IMPURITY
Structure of 11.ALPHA.,17,21-TRIHYDROXY-16.BETA.-METHYLPREGNA-1,4-DIENE-3,20-DIONE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Related Record Type Details
Structure of BETAMETHASONE
ACTIVE MOIETY
http://apps.who.int/phint/pdf/b/Jb.6.1.56.pdf
Name Property Type Amount Referenced Substance Defining Parameters References
Biological Half-life PHARMACOKINETIC
NIH
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