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Details

Stereochemistry ABSOLUTE
Molecular Formula C23H26N4O3
Molecular Weight 406.4775
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of SAMOTOLISIB

SMILES

CO[C@@H](C)CN1C(=O)N(C)C2=C1C3=CC(=CC=C3N=C2)C4=CC(=CN=C4)C(C)(C)O

InChI

InChIKey=ACCFLVVUVBJNGT-AWEZNQCLSA-N
InChI=1S/C23H26N4O3/c1-14(30-5)13-27-21-18-9-15(16-8-17(11-24-10-16)23(2,3)29)6-7-19(18)25-12-20(21)26(4)22(27)28/h6-12,14,29H,13H2,1-5H3/t14-/m0/s1

HIDE SMILES / InChI
Molecular Formula C23H26N4O3
Molecular Weight 406.4775
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 1 / 1
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

Unknown
86413
Substance Class Chemical
Created
by admin
on Sat Dec 16 08:10:00 UTC 2023
Edited
by admin
on Sat Dec 16 08:10:00 UTC 2023
Record UNII
C88817F47Y
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
SAMOTOLISIB
USAN   INN  
Official Name English
LY3023414
Code English
PI3K/MTOR INHIBITOR LY3023414
Common Name English
2H-IMIDAZO(4,5-C)QUINOLIN-2-ONE, 1,3-DIHYDRO-8-(5-(1-HYDROXY-1-METHYLETHYL)-3-PYRIDINYL)-1-((2S)-2-METHOXYPROPYL)-3-METHYL-
Systematic Name English
8-[5-(2-Hydroxypropan-2-yl)pyridin-3-yl]-1-[(2S)-2-methoxypropyl]-3-methyl-1,3-dihydro-2H-imidazo[4,5-c]quinolin-2-one
Systematic Name English
LY-3023414
Code English
samotolisib [INN]
Common Name English
Samotolisib [WHO-DD]
Common Name English
SAMOTOLISIB [USAN]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C1404
Created by admin on Sat Dec 16 08:10:00 UTC 2023 , Edited by admin on Sat Dec 16 08:10:00 UTC 2023
Code System Code Type Description
INN
10889
Created by admin on Sat Dec 16 08:10:00 UTC 2023 , Edited by admin on Sat Dec 16 08:10:00 UTC 2023
PRIMARY
DRUG BANK
DB12167
Created by admin on Sat Dec 16 08:10:00 UTC 2023 , Edited by admin on Sat Dec 16 08:10:00 UTC 2023
PRIMARY
ChEMBL
CHEMBL3544999
Created by admin on Sat Dec 16 08:10:00 UTC 2023 , Edited by admin on Sat Dec 16 08:10:00 UTC 2023
PRIMARY
PUBCHEM
57519748
Created by admin on Sat Dec 16 08:10:00 UTC 2023 , Edited by admin on Sat Dec 16 08:10:00 UTC 2023
PRIMARY
CAS
1386874-06-1
Created by admin on Sat Dec 16 08:10:00 UTC 2023 , Edited by admin on Sat Dec 16 08:10:00 UTC 2023
PRIMARY
USAN
EF-66
Created by admin on Sat Dec 16 08:10:00 UTC 2023 , Edited by admin on Sat Dec 16 08:10:00 UTC 2023
PRIMARY
FDA UNII
C88817F47Y
Created by admin on Sat Dec 16 08:10:00 UTC 2023 , Edited by admin on Sat Dec 16 08:10:00 UTC 2023
PRIMARY
NCI_THESAURUS
C121817
Created by admin on Sat Dec 16 08:10:00 UTC 2023 , Edited by admin on Sat Dec 16 08:10:00 UTC 2023
PRIMARY
SMS_ID
100000177957
Created by admin on Sat Dec 16 08:10:00 UTC 2023 , Edited by admin on Sat Dec 16 08:10:00 UTC 2023
PRIMARY
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Structure of SAMOTOLISIB
ACTIVE MOIETY
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