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Details

Stereochemistry RACEMIC
Molecular Formula C16H13ClN2O2
Molecular Weight 300.74
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of TEMAZEPAM

SMILES

CN1C2=C(C=C(Cl)C=C2)C(=NC(O)C1=O)C3=CC=CC=C3

InChI

InChIKey=SEQDDYPDSLOBDC-UHFFFAOYSA-N
InChI=1S/C16H13ClN2O2/c1-19-13-8-7-11(17)9-12(13)14(18-15(20)16(19)21)10-5-3-2-4-6-10/h2-9,15,20H,1H3

HIDE SMILES / InChI
Molecular Formula C16H13ClN2O2
Molecular Weight 300.74
Charge 0
Count
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

Approval Year

Unknown
86413
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:25:51 UTC 2023
Edited
by admin
on Fri Dec 15 15:25:51 UTC 2023
Record UNII
CHB1QD2QSS
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
TEMAZEPAM
EP   INN   MART.   MI   ORANGE BOOK   USAN   USP   VANDF   WHO-DD  
USAN   INN  
Official Name English
NSC-246303
Code English
TEMAZEPAM [USAN]
Common Name English
(RS)-TEMAZEPAM
Common Name English
WY-3917
Code English
TEMAZEPAM [ORANGE BOOK]
Common Name English
(±)-TEMAZEPAM
Common Name English
7-Chloro-1,3-dihydro-3-hydroxy-1-methyl-5-phenyl-2H-1,4-benzodiazepin-2-one
Systematic Name English
TEMAZEPAM [USP MONOGRAPH]
Common Name English
Temazepam [WHO-DD]
Common Name English
RESTORIL
Brand Name English
TEMAZEPAM [MI]
Common Name English
temazepam [INN]
Common Name English
TEMAZEPAM [MART.]
Common Name English
TEMAZEPAM [VANDF]
Common Name English
TEMAZEPAM CIV [USP-RS]
Common Name English
TEMAZEPAM CIV
USP-RS  
Common Name English
TEMAZEPAM [EP MONOGRAPH]
Common Name English
2H-1,4-BENZODIAZEPIN-2-ONE, 7-CHLORO-1,3-DIHYDRO-3-HYDROXY-1-METHYL-5-PHENYL-
Systematic Name English
TEMAZEPAM [IARC]
Common Name English
Classification Tree Code System Code
WHO-ATC N05CD07
Created by admin on Fri Dec 15 15:25:52 UTC 2023 , Edited by admin on Fri Dec 15 15:25:52 UTC 2023
LIVERTOX NBK548556
Created by admin on Fri Dec 15 15:25:52 UTC 2023 , Edited by admin on Fri Dec 15 15:25:52 UTC 2023
NDF-RT N0000175694
Created by admin on Fri Dec 15 15:25:52 UTC 2023 , Edited by admin on Fri Dec 15 15:25:52 UTC 2023
DEA NO. 2925
Created by admin on Fri Dec 15 15:25:52 UTC 2023 , Edited by admin on Fri Dec 15 15:25:52 UTC 2023
NDF-RT N0000007542
Created by admin on Fri Dec 15 15:25:52 UTC 2023 , Edited by admin on Fri Dec 15 15:25:52 UTC 2023
NCI_THESAURUS C1012
Created by admin on Fri Dec 15 15:25:52 UTC 2023 , Edited by admin on Fri Dec 15 15:25:52 UTC 2023
WHO-VATC QN05CD07
Created by admin on Fri Dec 15 15:25:52 UTC 2023 , Edited by admin on Fri Dec 15 15:25:52 UTC 2023
Code System Code Type Description
NCI_THESAURUS
C29488
Created by admin on Fri Dec 15 15:25:52 UTC 2023 , Edited by admin on Fri Dec 15 15:25:52 UTC 2023
PRIMARY
RXCUI
10355
Created by admin on Fri Dec 15 15:25:52 UTC 2023 , Edited by admin on Fri Dec 15 15:25:52 UTC 2023
PRIMARY RxNorm
CAS
846-50-4
Created by admin on Fri Dec 15 15:25:52 UTC 2023 , Edited by admin on Fri Dec 15 15:25:52 UTC 2023
PRIMARY
PUBCHEM
5391
Created by admin on Fri Dec 15 15:25:52 UTC 2023 , Edited by admin on Fri Dec 15 15:25:52 UTC 2023
PRIMARY
ECHA (EC/EINECS)
212-688-1
Created by admin on Fri Dec 15 15:25:52 UTC 2023 , Edited by admin on Fri Dec 15 15:25:52 UTC 2023
PRIMARY
DRUG BANK
DB00231
Created by admin on Fri Dec 15 15:25:52 UTC 2023 , Edited by admin on Fri Dec 15 15:25:52 UTC 2023
PRIMARY
SMS_ID
100000092289
Created by admin on Fri Dec 15 15:25:52 UTC 2023 , Edited by admin on Fri Dec 15 15:25:52 UTC 2023
PRIMARY
MESH
D013693
Created by admin on Fri Dec 15 15:25:52 UTC 2023 , Edited by admin on Fri Dec 15 15:25:52 UTC 2023
PRIMARY
NSC
246303
Created by admin on Fri Dec 15 15:25:52 UTC 2023 , Edited by admin on Fri Dec 15 15:25:52 UTC 2023
PRIMARY
EPA CompTox
DTXSID8021309
Created by admin on Fri Dec 15 15:25:52 UTC 2023 , Edited by admin on Fri Dec 15 15:25:52 UTC 2023
PRIMARY
WIKIPEDIA
TEMAZEPAM
Created by admin on Fri Dec 15 15:25:52 UTC 2023 , Edited by admin on Fri Dec 15 15:25:52 UTC 2023
PRIMARY
DRUG CENTRAL
2585
Created by admin on Fri Dec 15 15:25:52 UTC 2023 , Edited by admin on Fri Dec 15 15:25:52 UTC 2023
PRIMARY
INN
2753
Created by admin on Fri Dec 15 15:25:52 UTC 2023 , Edited by admin on Fri Dec 15 15:25:52 UTC 2023
PRIMARY
DAILYMED
CHB1QD2QSS
Created by admin on Fri Dec 15 15:25:52 UTC 2023 , Edited by admin on Fri Dec 15 15:25:52 UTC 2023
PRIMARY
LACTMED
Temazepam
Created by admin on Fri Dec 15 15:25:52 UTC 2023 , Edited by admin on Fri Dec 15 15:25:52 UTC 2023
PRIMARY
MERCK INDEX
m10545
Created by admin on Fri Dec 15 15:25:52 UTC 2023 , Edited by admin on Fri Dec 15 15:25:52 UTC 2023
PRIMARY Merck Index
FDA UNII
CHB1QD2QSS
Created by admin on Fri Dec 15 15:25:52 UTC 2023 , Edited by admin on Fri Dec 15 15:25:52 UTC 2023
PRIMARY
ChEMBL
CHEMBL967
Created by admin on Fri Dec 15 15:25:52 UTC 2023 , Edited by admin on Fri Dec 15 15:25:52 UTC 2023
PRIMARY
RS_ITEM_NUM
1643408
Created by admin on Fri Dec 15 15:25:52 UTC 2023 , Edited by admin on Fri Dec 15 15:25:52 UTC 2023
PRIMARY
IUPHAR
7300
Created by admin on Fri Dec 15 15:25:52 UTC 2023 , Edited by admin on Fri Dec 15 15:25:52 UTC 2023
PRIMARY
EVMPD
SUB10880MIG
Created by admin on Fri Dec 15 15:25:52 UTC 2023 , Edited by admin on Fri Dec 15 15:25:52 UTC 2023
PRIMARY
Related Record Type Details
Structure of TEMAZEPAM HYDROCHLORIDE
SALT/SOLVATE -> PARENT
Structure of TEMAZEPAM
BASIS OF STRENGTH->SUBSTANCE
ASSAY (HPLC)
EP
PLASMA PROTEIN FRACTION (HUMAN)
BINDER->LIGAND
Structure of TEMAZEPAM
BASIS OF STRENGTH->SUBSTANCE
ASSAY (HPLC)
USP
Structure of TEMAZEPAM SULFATE
SALT/SOLVATE -> PARENT
Related Record Type Details
Structure of TEMAZEPAM GLUCURONIDE
METABOLITE INACTIVE -> PARENT
Structure of DIAZEPAM
PARENT -> METABOLITE ACTIVE
Structure of TEMAZEPAM GLUCURONIDE
METABOLITE INACTIVE -> PARENT
MAJOR
PLASMA; URINE
Structure of OXAZEPAM
METABOLITE -> PARENT
TRACE IN URINE; NOT IN PLASMA
MINOR
URINE
Structure of OXAZEPAM GLUCURONIDE
METABOLITE INACTIVE -> PARENT
MAJOR
PLASMA; URINE
Related Record Type Details
Structure of O-METHYL TEMAZEPAM
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of DIAZEPAM N-OXIDE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of OXAZEPAM
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of 3-OXO-4,5-DIHYDRO-4-METHYL TEMAZEPAM
IMPURITY -> PARENT
For the calculation of contents, multiply the peak areas by 3.1
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of 3-OXO-4,5-DIHYDRO-4-METHYL TEMAZEPAM
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of 3-OXO-4,5-DIHYDRO TEMAZEPAM
IMPURITY -> PARENT
For the calculation of contents, multiply the peak areas by 3.2
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of TEMAZEPAM ACETATE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of 5-CHLORO-2-METHYLAMINOBENZOPHENONE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of 5-CHLORO-2-METHYLAMINOBENZOPHENONE
IMPURITY -> PARENT
Dissolve 0.400 g in methylene chloride R and dilute to 20.0 mL with the same solvent. The absorbance (2.2.25) is not greater than 0.30 at 409 nm
IMPURITY (UV)
EP
Structure of OXAZEPAM
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of 3-OXO-4,5-DIHYDRO TEMAZEPAM
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of TEMAZEPAM ACETATE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of O-METHYL TEMAZEPAM
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of DIAZEPAM N-OXIDE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Related Record Type Details
Structure of TEMAZEPAM
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