FLUCYTOSINE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C4H4FN3O
Molecular Weight	129.0925
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of FLUCYTOSINE

Structure Search

SMILES

NC1=NC(=O)NC=C1F

InChI

InChIKey=XRECTZIEBJDKEO-UHFFFAOYSA-N

InChI=1S/C4H4FN3O/c5-2-1-7-4(9)8-3(2)6/h1H,(H3,6,7,8,9)

HIDE SMILES / InChI

Molecular Formula	C4H4FN3O
Molecular Weight	129.0925
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:02:47 UTC 2023` Edited by `admin` on `Fri Dec 15 15:02:47 UTC 2023`
Record UNII	D83282DT06
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

FLUCYTOSINE

Official Name

English

5-FLUOROCYTOSINE [WHO-IP]

Common Name

English

RO-29915

Code

English

RO 2-9915

Code

English

ANCOBON

Brand Name

English

FLUCYTOSINE [WHO-IP]

Common Name

English

5-Fluorocytosine

Systematic Name

English

FLUCYTOSINE [USP IMPURITY]

Common Name

English

FLUOROCYTOSINE

Systematic Name

English

FLUCYTOSINE [MI]

Common Name

English

NSC-103805

Code

English

RO-2-9915

Code

English

FLUCYTOSINE [HSDB]

Common Name

English

FLUCYTOSINE [USAN]

Common Name

English

Flucytosine [WHO-DD]

Common Name

English

FLUCYTOSINE [ORANGE BOOK]

Common Name

English

CYTOSINE, 5-FLUORO-

Systematic Name

English

4-AMINO-5-FLUOROPYRIMIDIN-2(1H)-ONE [WHO-IP]

Systematic Name

English

FLUCYTOSINE [EP MONOGRAPH]

Common Name

English

FLUCYTOSINE [MART.]

Common Name

English

FLUCYTOSINE [USP-RS]

Common Name

English

FLUCYTOSINE [USP MONOGRAPH]

Common Name

English

FLUCYTOSINE [JAN]

Common Name

English

EMTRICITABINE IMPURITY E [WHO-IP]

Common Name

English

FLUCYTOSINUM [WHO-IP LATIN]

Common Name

English

flucytosine [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C1557

Created by admin on Fri Dec 15 15:02:48 UTC 2023 , Edited by admin on Fri Dec 15 15:02:48 UTC 2023

WHO-ATC

D01AE21

Created by admin on Fri Dec 15 15:02:48 UTC 2023 , Edited by admin on Fri Dec 15 15:02:48 UTC 2023

WHO-ATC

J02AX01

Created by admin on Fri Dec 15 15:02:48 UTC 2023 , Edited by admin on Fri Dec 15 15:02:48 UTC 2023

EU-Orphan Drug

EU/3/18/1978

Created by admin on Fri Dec 15 15:02:48 UTC 2023 , Edited by admin on Fri Dec 15 15:02:48 UTC 2023

WHO-VATC

QJ02AX01

Created by admin on Fri Dec 15 15:02:48 UTC 2023 , Edited by admin on Fri Dec 15 15:02:48 UTC 2023

NDF-RT

N0000175467

Created by admin on Fri Dec 15 15:02:48 UTC 2023 , Edited by admin on Fri Dec 15 15:02:48 UTC 2023

NDF-RT

N0000175459

Created by admin on Fri Dec 15 15:02:48 UTC 2023 , Edited by admin on Fri Dec 15 15:02:48 UTC 2023

WHO-VATC

QD01AE21

Created by admin on Fri Dec 15 15:02:48 UTC 2023 , Edited by admin on Fri Dec 15 15:02:48 UTC 2023

NDF-RT

N0000175459

Created by admin on Fri Dec 15 15:02:48 UTC 2023 , Edited by admin on Fri Dec 15 15:02:48 UTC 2023

LIVERTOX

NBK548624

Created by admin on Fri Dec 15 15:02:48 UTC 2023 , Edited by admin on Fri Dec 15 15:02:48 UTC 2023

NDF-RT

N0000175459

Created by admin on Fri Dec 15 15:02:48 UTC 2023 , Edited by admin on Fri Dec 15 15:02:48 UTC 2023

FDA ORPHAN DRUG

327910

Created by admin on Fri Dec 15 15:02:48 UTC 2023 , Edited by admin on Fri Dec 15 15:02:48 UTC 2023

WHO-ESSENTIAL MEDICINES LIST

6.3

Created by admin on Fri Dec 15 15:02:48 UTC 2023 , Edited by admin on Fri Dec 15 15:02:48 UTC 2023

Code System Code Type Description

DAILYMED

D83282DT06

Created by admin on Fri Dec 15 15:02:48 UTC 2023 , Edited by admin on Fri Dec 15 15:02:48 UTC 2023

PRIMARY

WHO INTERNATIONAL PHARMACOPEIA

FLUCYTOSINE

Created by admin on Fri Dec 15 15:02:48 UTC 2023 , Edited by admin on Fri Dec 15 15:02:48 UTC 2023

PRIMARY

Description: A white or almost white, crystalline powder; odourless or almost odourless. Solubility: Sparingly soluble in water; slightly soluble in ethanol (~750 g/l) TS; practically insoluble in ether R. Category: Antifungal drug. Storage: Flucytosine should be kept in a tightly closed container, protected from light.Additional information: Flucytosine melts at about 295 ?C. Definition: Flucytosine contains not less than 98.5% and not more than 101.0% of C4H4FN3O, calculated with reference to the dried substance.

CHEBI

5100

Created by admin on Fri Dec 15 15:02:48 UTC 2023 , Edited by admin on Fri Dec 15 15:02:48 UTC 2023

PRIMARY

NSC

103805

Created by admin on Fri Dec 15 15:02:48 UTC 2023 , Edited by admin on Fri Dec 15 15:02:48 UTC 2023

PRIMARY

RS_ITEM_NUM

1272000

Created by admin on Fri Dec 15 15:02:48 UTC 2023 , Edited by admin on Fri Dec 15 15:02:48 UTC 2023

PRIMARY

SMS_ID

100000091594

Created by admin on Fri Dec 15 15:02:48 UTC 2023 , Edited by admin on Fri Dec 15 15:02:48 UTC 2023

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DRUG BANK

DB01099

Created by admin on Fri Dec 15 15:02:48 UTC 2023 , Edited by admin on Fri Dec 15 15:02:48 UTC 2023

PRIMARY

FDA UNII

D83282DT06

Created by admin on Fri Dec 15 15:02:48 UTC 2023 , Edited by admin on Fri Dec 15 15:02:48 UTC 2023

PRIMARY

NCI_THESAURUS

C501

Created by admin on Fri Dec 15 15:02:48 UTC 2023 , Edited by admin on Fri Dec 15 15:02:48 UTC 2023

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PUBCHEM

3366

Created by admin on Fri Dec 15 15:02:48 UTC 2023 , Edited by admin on Fri Dec 15 15:02:48 UTC 2023

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WIKIPEDIA

FLUCYTOSINE

Created by admin on Fri Dec 15 15:02:48 UTC 2023 , Edited by admin on Fri Dec 15 15:02:48 UTC 2023

PRIMARY

ChEMBL

CHEMBL1463

Created by admin on Fri Dec 15 15:02:48 UTC 2023 , Edited by admin on Fri Dec 15 15:02:48 UTC 2023

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CAS

2022-85-7

Created by admin on Fri Dec 15 15:02:48 UTC 2023 , Edited by admin on Fri Dec 15 15:02:48 UTC 2023

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DRUG CENTRAL

1188

Created by admin on Fri Dec 15 15:02:48 UTC 2023 , Edited by admin on Fri Dec 15 15:02:48 UTC 2023

PRIMARY

ECHA (EC/EINECS)

217-968-7

Created by admin on Fri Dec 15 15:02:48 UTC 2023 , Edited by admin on Fri Dec 15 15:02:48 UTC 2023

PRIMARY

EPA CompTox

DTXSID3023059

Created by admin on Fri Dec 15 15:02:48 UTC 2023 , Edited by admin on Fri Dec 15 15:02:48 UTC 2023

PRIMARY

MERCK INDEX

m5426

Created by admin on Fri Dec 15 15:02:48 UTC 2023 , Edited by admin on Fri Dec 15 15:02:48 UTC 2023

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Merck Index

INN

2729

Created by admin on Fri Dec 15 15:02:48 UTC 2023 , Edited by admin on Fri Dec 15 15:02:48 UTC 2023

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HSDB

3082

Created by admin on Fri Dec 15 15:02:48 UTC 2023 , Edited by admin on Fri Dec 15 15:02:48 UTC 2023

PRIMARY

EVMPD

SUB07676MIG

Created by admin on Fri Dec 15 15:02:48 UTC 2023 , Edited by admin on Fri Dec 15 15:02:48 UTC 2023

PRIMARY

MESH

D005437

Created by admin on Fri Dec 15 15:02:48 UTC 2023 , Edited by admin on Fri Dec 15 15:02:48 UTC 2023

PRIMARY

RXCUI

4451

Created by admin on Fri Dec 15 15:02:48 UTC 2023 , Edited by admin on Fri Dec 15 15:02:48 UTC 2023

PRIMARY

RxNorm

Related Record Type Details


					D83282DT06

BASIS OF STRENGTH->SUBSTANCE

Interaction Type:

ASSAY (TITRATION)

Qualification:

EP

Amount:


					6D53G0FD0Z

PLASMA PROTEIN FRACTION (HUMAN)

BINDER->LIGAND

Interaction Type:

BINDING

Amount:

Related Record Type Details


					15FS54053U

2-ETHOXY-5-FLUOROURACIL

IMPURITY -> PARENT

Comments:

For the calculation of contents, multiply the peak areas by 0.6

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					G70B4ETF4S

PARENT -> IMPURITY


					U3P01618RT

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:

Related Record Type Details


					D83282DT06

ACTIVE MOIETY

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Volume of Distribution	PHARMACOKINETIC

Biological Half-life	PHARMACOKINETIC