LEUPROLIDE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C59H84N16O12
Molecular Weight	1209.3983
Optical Activity	UNSPECIFIED
Defined Stereocenters	9 / 9
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of LEUPROLIDE

Structure Search

SMILES

CCNC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](CC2=CC=C(O)C=C2)NC(=O)[C@H](CO)NC(=O)[C@H](CC3=CNC4=C3C=CC=C4)NC(=O)[C@H](CC5=CNC=N5)NC(=O)[C@@H]6CCC(=O)N6

InChI

InChIKey=GFIJNRVAKGFPGQ-LIJARHBVSA-N

InChI=1S/C59H84N16O12/c1-6-63-57(86)48-14-10-22-75(48)58(87)41(13-9-21-64-59(60)61)68-51(80)42(23-32(2)3)69-52(81)43(24-33(4)5)70-53(82)44(25-34-15-17-37(77)18-16-34)71-56(85)47(30-76)74-54(83)45(26-35-28-65-39-12-8-7-11-38(35)39)72-55(84)46(27-36-29-62-31-66-36)73-50(79)40-19-20-49(78)67-40/h7-8,11-12,15-18,28-29,31-33,40-48,65,76-77H,6,9-10,13-14,19-27,30H2,1-5H3,(H,62,66)(H,63,86)(H,67,78)(H,68,80)(H,69,81)(H,70,82)(H,71,85)(H,72,84)(H,73,79)(H,74,83)(H4,60,61,64)/t40-,41-,42-,43+,44-,45-,46-,47-,48-/m0/s1

HIDE SMILES / InChI

Molecular Formula	C59H84N16O12
Molecular Weight	1209.3983
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	9 / 9
E/Z Centers	3
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Sat Dec 16 16:53:43 UTC 2023` Edited by `admin` on `Sat Dec 16 16:53:43 UTC 2023`
Record UNII	EFY6W0M8TG
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

LEUPROLIDE

Common Name

English

LEUPRORELIN SLOW RELEASE

Common Name

English

leuprorelin [INN]

Common Name

English

LEUPROLIDE [HSDB]

Common Name

English

LEUPRORELIN

Official Name

English

TAP-144 FREE BASE

Code

English

Leuprorelin [WHO-DD]

Common Name

English

LEUPORELIN

Common Name

English

NSC-377526

Code

English

LEUPROLIDE [MI]

Common Name

English

LEUPROLIDE [VANDF]

Common Name

English

CKD-841

Code

English

ABBOTT-43818 FREE BASE

Code

English

(-)-LEUPROLIDE

Common Name

English

LEUPRORELIN [MART.]

Common Name

English

LEUPRORELIN [EP MONOGRAPH]

Common Name

English

5-OXO-L-PROLYL-L-HISTIDYL-L-TRYPTOPHYL-L-SERYL-L-TRYOSYL-D-LEUCYL-L-LEUCYL-L-ARGINYL-N-ETHYL-L-PROLINAMIDE

Common Name

English

PGLU-HIS-TRP-SER-TYR-D-LEU-LEU-ARG-PRO-NHC2H5

Common Name

English

Classification Tree Code System Code

WHO-ATC

L02AE51

Created by admin on Sat Dec 16 16:53:43 UTC 2023 , Edited by admin on Sat Dec 16 16:53:43 UTC 2023

NDF-RT

N0000175654

Created by admin on Sat Dec 16 16:53:43 UTC 2023 , Edited by admin on Sat Dec 16 16:53:43 UTC 2023

NDF-RT

N0000009332

Created by admin on Sat Dec 16 16:53:43 UTC 2023 , Edited by admin on Sat Dec 16 16:53:43 UTC 2023

WHO-VATC

QL02AE02

Created by admin on Sat Dec 16 16:53:43 UTC 2023 , Edited by admin on Sat Dec 16 16:53:43 UTC 2023

NDF-RT

N0000175655

Created by admin on Sat Dec 16 16:53:43 UTC 2023 , Edited by admin on Sat Dec 16 16:53:43 UTC 2023

NCI_THESAURUS

C1910

Created by admin on Sat Dec 16 16:53:43 UTC 2023 , Edited by admin on Sat Dec 16 16:53:43 UTC 2023

WHO-ATC

L02AE02

Created by admin on Sat Dec 16 16:53:43 UTC 2023 , Edited by admin on Sat Dec 16 16:53:43 UTC 2023

LIVERTOX

NBK548676

Created by admin on Sat Dec 16 16:53:43 UTC 2023 , Edited by admin on Sat Dec 16 16:53:43 UTC 2023

Code System Code Type Description

INN

5025

Created by admin on Sat Dec 16 16:53:43 UTC 2023 , Edited by admin on Sat Dec 16 16:53:43 UTC 2023

PRIMARY

WIKIPEDIA

Leuprorelin

Created by admin on Sat Dec 16 16:53:43 UTC 2023 , Edited by admin on Sat Dec 16 16:53:43 UTC 2023

PRIMARY

EVMPD

SUB08449MIG

Created by admin on Sat Dec 16 16:53:43 UTC 2023 , Edited by admin on Sat Dec 16 16:53:43 UTC 2023

PRIMARY

DAILYMED

EFY6W0M8TG

Created by admin on Sat Dec 16 16:53:43 UTC 2023 , Edited by admin on Sat Dec 16 16:53:43 UTC 2023

PRIMARY

NCI_THESAURUS

C62042

Created by admin on Sat Dec 16 16:53:43 UTC 2023 , Edited by admin on Sat Dec 16 16:53:43 UTC 2023

PRIMARY

RXCUI

42375

Created by admin on Sat Dec 16 16:53:43 UTC 2023 , Edited by admin on Sat Dec 16 16:53:43 UTC 2023

PRIMARY

RxNorm

MERCK INDEX

m6779

Created by admin on Sat Dec 16 16:53:43 UTC 2023 , Edited by admin on Sat Dec 16 16:53:43 UTC 2023

PRIMARY

Merck Index

FDA UNII

EFY6W0M8TG

Created by admin on Sat Dec 16 16:53:43 UTC 2023 , Edited by admin on Sat Dec 16 16:53:43 UTC 2023

PRIMARY

DRUG BANK

DB00007

Created by admin on Sat Dec 16 16:53:43 UTC 2023 , Edited by admin on Sat Dec 16 16:53:43 UTC 2023

PRIMARY

CAS

53714-56-0

Created by admin on Sat Dec 16 16:53:43 UTC 2023 , Edited by admin on Sat Dec 16 16:53:43 UTC 2023

PRIMARY

SMS_ID

100000088225

Created by admin on Sat Dec 16 16:53:43 UTC 2023 , Edited by admin on Sat Dec 16 16:53:43 UTC 2023

PRIMARY

IUPHAR

1175

Created by admin on Sat Dec 16 16:53:43 UTC 2023 , Edited by admin on Sat Dec 16 16:53:43 UTC 2023

PRIMARY

DRUG CENTRAL

1559

Created by admin on Sat Dec 16 16:53:43 UTC 2023 , Edited by admin on Sat Dec 16 16:53:43 UTC 2023

PRIMARY

EPA CompTox

DTXSID50872411

Created by admin on Sat Dec 16 16:53:43 UTC 2023 , Edited by admin on Sat Dec 16 16:53:43 UTC 2023

PRIMARY

PUBCHEM

657181

Created by admin on Sat Dec 16 16:53:43 UTC 2023 , Edited by admin on Sat Dec 16 16:53:43 UTC 2023

PRIMARY

ChEMBL

CHEMBL1201199

Created by admin on Sat Dec 16 16:53:43 UTC 2023 , Edited by admin on Sat Dec 16 16:53:43 UTC 2023

PRIMARY

NSC

377526

Created by admin on Sat Dec 16 16:53:43 UTC 2023 , Edited by admin on Sat Dec 16 16:53:43 UTC 2023

PRIMARY

CHEBI

6427

Created by admin on Sat Dec 16 16:53:43 UTC 2023 , Edited by admin on Sat Dec 16 16:53:43 UTC 2023

PRIMARY

HSDB

6518

Created by admin on Sat Dec 16 16:53:43 UTC 2023 , Edited by admin on Sat Dec 16 16:53:43 UTC 2023

PRIMARY

MESH

D016729

Created by admin on Sat Dec 16 16:53:43 UTC 2023 , Edited by admin on Sat Dec 16 16:53:43 UTC 2023

PRIMARY

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GONADOTROPIN-RELEASING HORMONE RECEPTOR

TARGET -> AGONIST

Amount:


					37JNS02E7V

LEUPROLIDE ACETATE

SALT/SOLVATE -> PARENT


					8E3C3C493W

LEUPROLIDE MESYLATE

SALT/SOLVATE -> PARENT

Related Record Type Details


					MU3XSB7W2O

LEUPROLIDE (5-9)

METABOLITE INACTIVE -> PARENT

Interaction Type:

MAJOR

Related Record Type Details


					EFY6W0M8TG

ACTIVE MOIETY

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Volume of Distribution	PHARMACOKINETIC				Males PHARMACOKINETIC