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Details

Stereochemistry RACEMIC
Molecular Formula C17H20N2S.ClH
Molecular Weight 320.88
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PROMETHAZINE HYDROCHLORIDE

SMILES

Cl.CC(CN1C2=C(SC3=C1C=CC=C3)C=CC=C2)N(C)C

InChI

InChIKey=XXPDBLUZJRXNNZ-UHFFFAOYSA-N
InChI=1S/C17H20N2S.ClH/c1-13(18(2)3)12-19-14-8-4-6-10-16(14)20-17-11-7-5-9-15(17)19;/h4-11,13H,12H2,1-3H3;1H

HIDE SMILES / InChI
Molecular Formula C17H20N2S
Molecular Weight 284.419
Charge 0
Count
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )
Molecular Formula ClH
Molecular Weight 36.461
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

Unknown
86413
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:33:17 UTC 2023
Edited
by admin
on Fri Dec 15 15:33:17 UTC 2023
Record UNII
R61ZEH7I1I
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
PROMETHAZINE HYDROCHLORIDE
EP   MART.   MI   ORANGE BOOK   USP   USP-RS   VANDF   WHO-DD   WHO-IP  
Common Name English
Promethazine hydrochloride [WHO-DD]
Common Name English
RP-3389
Code English
ZIPAN-50
Brand Name English
GENPHEN
Brand Name English
PROMETHAZINE HCL
Common Name English
PHENERGAN VC COMPONENT PROMETHAZINE HYDROCHLORIDE
Common Name English
10H-PHENOTHIAZINE-10-ETHANAMINE, N,N,.ALPHA.-TRIMETHYL-, MONOHYDROCHLORIDE, (±)-
Common Name English
PROMETHAZINE HYDROCHLORIDE [WHO-IP]
Common Name English
ANERGAN 25
Brand Name English
PROMETHAZINE HYDROCHLORIDE [JAN]
Common Name English
NSC-231688
Code English
PROMETHAZINE HYDROCHLORIDE [USP-RS]
Common Name English
DIPRAZINUM [WHO-IP]
Common Name English
PROMETHAZINE HYDROCHLORIDE COMPONENT OF PHERAZINE DM
Common Name English
PROMETHAZINE HYDROCHLORIDE [ORANGE BOOK]
Common Name English
MYMETHAZINE FORTIS
Brand Name English
PROMETHAZINE HYDROCHLORIDE COMPONENT OF PHERAZINE VC
Common Name English
PROMETHAZINE HYDROCHLORIDE COMPONENT OF PHENERGAN VC
Common Name English
PHERAZINE DM COMPONENT PROMETHAZINE HYDROCHLORIDE
Common Name English
PROMETHAZINE HYDROCHLORIDE [EP MONOGRAPH]
Common Name English
PROMETHEGAN
Brand Name English
PROMETHAZINE HYDROCHLORIDE [MART.]
Common Name English
PROMETHAZINE HYDROCHLORIDE [MI]
Common Name English
MEPERGAN COMPONENT PROMETHAZINE HYDROCHLORIDE
Common Name English
PRONASE [JAN]
Common Name English
(±)-10-(2-(DIMETHYLAMINO)PROPYL)PHENOTHIAZINE MONOHYDROCHLORIDE
Systematic Name English
PROMETH PLAIN
Brand Name English
PROMETH FORTIS
Brand Name English
MEPERGAN
Brand Name English
PROMETHAZINE HYDROCHLORIDE [USP IMPURITY]
Common Name English
PHENERGAN
Brand Name English
PROMETHAZINE HYDROCHLORIDE COMPONENT OF PROMETHAZINE VC
Common Name English
PROMETHAZINE HYDROCHLORIDE COMPONENT OF MEPERGAN
Common Name English
PROMETHACON
Brand Name English
PHERAZINE VC COMPONENT PROMETHAZINE HYDROCHLORIDE
Common Name English
PROMETHAZINE HYDROCHLORIDE COMPONENT OF PROMETHAZINE DM
Common Name English
PROMETHAZINE VC COMPONENT PROMETHAZINE HYDROCHLORIDE
Common Name English
REMSED
Brand Name English
ZIPAN-25
Brand Name English
PHANERGAN D
Common Name English
PROREX
Brand Name English
PROMETHAZINE HYDROCHLORIDE [VANDF]
Common Name English
PROMETHAZINI HYDROCHLORIDUM [WHO-IP LATIN]
Common Name English
10H-PHENOTHIAZINE-10-ETHANAMINE, N,N,.ALPHA.-TRIMETHYL-, MONOHYDROCHLORIDE
Common Name English
PROMETHAZINE DM COMPONENT PROMETHAZINE HYDROCHLORIDE
Common Name English
PROMETHAZINE HYDROCHLORIDE [USP MONOGRAPH]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C29756
Created by admin on Fri Dec 15 15:33:17 UTC 2023 , Edited by admin on Fri Dec 15 15:33:17 UTC 2023
NCI_THESAURUS C740
Created by admin on Fri Dec 15 15:33:17 UTC 2023 , Edited by admin on Fri Dec 15 15:33:17 UTC 2023
Code System Code Type Description
EVMPD
SUB04070MIG
Created by admin on Fri Dec 15 15:33:17 UTC 2023 , Edited by admin on Fri Dec 15 15:33:17 UTC 2023
PRIMARY
CHEBI
8462
Created by admin on Fri Dec 15 15:33:17 UTC 2023 , Edited by admin on Fri Dec 15 15:33:17 UTC 2023
PRIMARY
NCI_THESAURUS
C45907
Created by admin on Fri Dec 15 15:33:17 UTC 2023 , Edited by admin on Fri Dec 15 15:33:17 UTC 2023
PRIMARY
CAS
88208-28-0
Created by admin on Fri Dec 15 15:33:17 UTC 2023 , Edited by admin on Fri Dec 15 15:33:17 UTC 2023
SUPERSEDED
FDA UNII
R61ZEH7I1I
Created by admin on Fri Dec 15 15:33:17 UTC 2023 , Edited by admin on Fri Dec 15 15:33:17 UTC 2023
PRIMARY
WHO INTERNATIONAL PHARMACOPEIA
PROMETHAZINE HYDROCHLORIDE
Created by admin on Fri Dec 15 15:33:17 UTC 2023 , Edited by admin on Fri Dec 15 15:33:17 UTC 2023
PRIMARY Description: A white or faintly yellowish, crystalline powder; odourless or almost odourless. Solubility: Very soluble in water; freely soluble in ethanol (~750 g/l) TS; practically insoluble in ether R. Category: Antiemetic drug. Storage: Promethazine hydrochloride should be kept in a tightly closed container, protected from light. Additional information: On prolonged exposure to air, Promethazine hydrochloride slowly oxidizes and acquires a blue colour. Even in the absence of light, it is gradually degraded on exposure to a humid atmosphere, the decomposition being faster at higher temperatures. Definition: Promethazine hydrochloride contains not less than 98.5% and not more than 101.0% of C17H20N2S,HCl, calculatedwith reference to the dried substance.
CAS
58-33-3
Created by admin on Fri Dec 15 15:33:17 UTC 2023 , Edited by admin on Fri Dec 15 15:33:17 UTC 2023
PRIMARY
NSC
231688
Created by admin on Fri Dec 15 15:33:17 UTC 2023 , Edited by admin on Fri Dec 15 15:33:17 UTC 2023
PRIMARY
RS_ITEM_NUM
1570009
Created by admin on Fri Dec 15 15:33:17 UTC 2023 , Edited by admin on Fri Dec 15 15:33:17 UTC 2023
PRIMARY
PUBCHEM
6014
Created by admin on Fri Dec 15 15:33:17 UTC 2023 , Edited by admin on Fri Dec 15 15:33:17 UTC 2023
PRIMARY
ECHA (EC/EINECS)
200-375-2
Created by admin on Fri Dec 15 15:33:17 UTC 2023 , Edited by admin on Fri Dec 15 15:33:17 UTC 2023
PRIMARY
SMS_ID
100000091355
Created by admin on Fri Dec 15 15:33:17 UTC 2023 , Edited by admin on Fri Dec 15 15:33:17 UTC 2023
PRIMARY
EPA CompTox
DTXSID3021192
Created by admin on Fri Dec 15 15:33:17 UTC 2023 , Edited by admin on Fri Dec 15 15:33:17 UTC 2023
PRIMARY
CAS
16639-38-6
Created by admin on Fri Dec 15 15:33:17 UTC 2023 , Edited by admin on Fri Dec 15 15:33:17 UTC 2023
SUPERSEDED
DRUG BANK
DBSALT000427
Created by admin on Fri Dec 15 15:33:17 UTC 2023 , Edited by admin on Fri Dec 15 15:33:17 UTC 2023
PRIMARY
DAILYMED
R61ZEH7I1I
Created by admin on Fri Dec 15 15:33:17 UTC 2023 , Edited by admin on Fri Dec 15 15:33:17 UTC 2023
PRIMARY
MERCK INDEX
m9171
Created by admin on Fri Dec 15 15:33:17 UTC 2023 , Edited by admin on Fri Dec 15 15:33:17 UTC 2023
PRIMARY Merck Index
ChEMBL
CHEMBL643
Created by admin on Fri Dec 15 15:33:17 UTC 2023 , Edited by admin on Fri Dec 15 15:33:17 UTC 2023
PRIMARY
RXCUI
142445
Created by admin on Fri Dec 15 15:33:17 UTC 2023 , Edited by admin on Fri Dec 15 15:33:17 UTC 2023
PRIMARY RxNorm
Related Record Type Details
Structure of PROMETHAZINE
PARENT -> SALT/SOLVATE
Structure of PROMETHAZINE HYDROCHLORIDE
BASIS OF STRENGTH->SUBSTANCE
ASSAY (TITRATION)
EP
Structure of PROMETHAZINE HYDROCHLORIDE
BASIS OF STRENGTH->SUBSTANCE
ASSAY (TITRATION)
USP
Related Record Type Details
Structure of PROMETHAZINE SULFOXIDE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of PHENOTHIAZINE
IMPURITY -> PARENT
For the calculation of contents, multiply the peak areas by 0.5
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of ISOPROMETHAZINE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of N-DEMETHYLPROMETHAZINE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Related Record Type Details
Structure of PROMETHAZINE
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