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Details

Stereochemistry ACHIRAL
Molecular Formula C15H12N2O2
Molecular Weight 252.268
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of OXCARBAZEPINE

SMILES

NC(=O)N1C2=C(CC(=O)C3=C1C=CC=C3)C=CC=C2

InChI

InChIKey=CTRLABGOLIVAIY-UHFFFAOYSA-N
InChI=1S/C15H12N2O2/c16-15(19)17-12-7-3-1-5-10(12)9-14(18)11-6-2-4-8-13(11)17/h1-8H,9H2,(H2,16,19)

HIDE SMILES / InChI
Molecular Formula C15H12N2O2
Molecular Weight 252.268
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

Unknown
86413
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:06:08 UTC 2023
Edited
by admin
on Fri Dec 15 15:06:08 UTC 2023
Record UNII
VZI5B1W380
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
OXCARBAZEPINE
HSDB   INN   MART.   MI   ORANGE BOOK   USAN   USP   USP-RS   VANDF   WHO-DD  
USAN   INN  
Official Name English
OXCARBAZEPINE [VANDF]
Common Name English
TRILEPTAL
Common Name English
oxcarbazepine [INN]
Common Name English
OXCARBAMAZEPINE
Common Name English
OXCARBAZEPINE [HSDB]
Common Name English
OXCARBAZEPINE [USP MONOGRAPH]
Common Name English
KIN-493
Code English
OXCARBAZEPINE [USAN]
Common Name English
OXCARBAZEPINE [MI]
Common Name English
OXCARBAZEPINE [JAN]
Common Name English
GP-47680
Code English
Oxcarbazepine [WHO-DD]
Common Name English
NSC-758693
Code English
OXCARBAZEPINE [EP MONOGRAPH]
Common Name English
SPN-804
Code English
10,11-DIHYDRO-10-OXO-5H-DIBENZ(B,F)AZEPINE-5-CARBOXAMIDE
Systematic Name English
OXCARBAZEPINE [ORANGE BOOK]
Common Name English
OXCARBAZEPINE [USP-RS]
Common Name English
OXCARBAZEPINE [MART.]
Common Name English
5H-DIBENZ(B,F)AZEPINE-5-CARBOXAMIDE, 10,11-DIHYDRO-10-OXO-
Systematic Name English
OXTELLAR XR
Brand Name English
Classification Tree Code System Code
NCI_THESAURUS C264
Created by admin on Fri Dec 15 15:06:08 UTC 2023 , Edited by admin on Fri Dec 15 15:06:08 UTC 2023
LIVERTOX NBK548414
Created by admin on Fri Dec 15 15:06:08 UTC 2023 , Edited by admin on Fri Dec 15 15:06:08 UTC 2023
NDF-RT N0000008486
Created by admin on Fri Dec 15 15:06:08 UTC 2023 , Edited by admin on Fri Dec 15 15:06:08 UTC 2023
NDF-RT N0000175753
Created by admin on Fri Dec 15 15:06:08 UTC 2023 , Edited by admin on Fri Dec 15 15:06:08 UTC 2023
WHO-VATC QN03AF02
Created by admin on Fri Dec 15 15:06:08 UTC 2023 , Edited by admin on Fri Dec 15 15:06:08 UTC 2023
WHO-ATC N03AF02
Created by admin on Fri Dec 15 15:06:08 UTC 2023 , Edited by admin on Fri Dec 15 15:06:08 UTC 2023
Code System Code Type Description
DRUG BANK
DB00776
Created by admin on Fri Dec 15 15:06:08 UTC 2023 , Edited by admin on Fri Dec 15 15:06:08 UTC 2023
PRIMARY
CAS
28721-07-5
Created by admin on Fri Dec 15 15:06:08 UTC 2023 , Edited by admin on Fri Dec 15 15:06:08 UTC 2023
PRIMARY
EVMPD
SUB32960
Created by admin on Fri Dec 15 15:06:08 UTC 2023 , Edited by admin on Fri Dec 15 15:06:08 UTC 2023
PRIMARY
INN
4585
Created by admin on Fri Dec 15 15:06:08 UTC 2023 , Edited by admin on Fri Dec 15 15:06:08 UTC 2023
PRIMARY
WIKIPEDIA
OXCARBAZEPINE
Created by admin on Fri Dec 15 15:06:08 UTC 2023 , Edited by admin on Fri Dec 15 15:06:08 UTC 2023
PRIMARY
EVMPD
SUB09510MIG
Created by admin on Fri Dec 15 15:06:08 UTC 2023 , Edited by admin on Fri Dec 15 15:06:08 UTC 2023
PRIMARY
USAN
MM-02
Created by admin on Fri Dec 15 15:06:08 UTC 2023 , Edited by admin on Fri Dec 15 15:06:08 UTC 2023
PRIMARY
HSDB
7524
Created by admin on Fri Dec 15 15:06:08 UTC 2023 , Edited by admin on Fri Dec 15 15:06:08 UTC 2023
PRIMARY
LACTMED
Oxcarbazepine
Created by admin on Fri Dec 15 15:06:08 UTC 2023 , Edited by admin on Fri Dec 15 15:06:08 UTC 2023
PRIMARY
IUPHAR
7254
Created by admin on Fri Dec 15 15:06:08 UTC 2023 , Edited by admin on Fri Dec 15 15:06:08 UTC 2023
PRIMARY
ECHA (EC/EINECS)
249-188-8
Created by admin on Fri Dec 15 15:06:08 UTC 2023 , Edited by admin on Fri Dec 15 15:06:08 UTC 2023
PRIMARY
DAILYMED
VZI5B1W380
Created by admin on Fri Dec 15 15:06:08 UTC 2023 , Edited by admin on Fri Dec 15 15:06:08 UTC 2023
PRIMARY
MESH
C036006
Created by admin on Fri Dec 15 15:06:08 UTC 2023 , Edited by admin on Fri Dec 15 15:06:08 UTC 2023
PRIMARY
RS_ITEM_NUM
1483152
Created by admin on Fri Dec 15 15:06:08 UTC 2023 , Edited by admin on Fri Dec 15 15:06:08 UTC 2023
PRIMARY
FDA UNII
VZI5B1W380
Created by admin on Fri Dec 15 15:06:08 UTC 2023 , Edited by admin on Fri Dec 15 15:06:08 UTC 2023
PRIMARY
DRUG CENTRAL
2017
Created by admin on Fri Dec 15 15:06:08 UTC 2023 , Edited by admin on Fri Dec 15 15:06:08 UTC 2023
PRIMARY
RXCUI
32624
Created by admin on Fri Dec 15 15:06:08 UTC 2023 , Edited by admin on Fri Dec 15 15:06:08 UTC 2023
PRIMARY RxNorm
NSC
758693
Created by admin on Fri Dec 15 15:06:08 UTC 2023 , Edited by admin on Fri Dec 15 15:06:08 UTC 2023
PRIMARY
SMS_ID
100000092224
Created by admin on Fri Dec 15 15:06:08 UTC 2023 , Edited by admin on Fri Dec 15 15:06:08 UTC 2023
PRIMARY
PUBCHEM
34312
Created by admin on Fri Dec 15 15:06:08 UTC 2023 , Edited by admin on Fri Dec 15 15:06:08 UTC 2023
PRIMARY
CHEBI
7824
Created by admin on Fri Dec 15 15:06:08 UTC 2023 , Edited by admin on Fri Dec 15 15:06:08 UTC 2023
PRIMARY
MERCK INDEX
m8298
Created by admin on Fri Dec 15 15:06:08 UTC 2023 , Edited by admin on Fri Dec 15 15:06:08 UTC 2023
PRIMARY Merck Index
EPA CompTox
DTXSID0045703
Created by admin on Fri Dec 15 15:06:08 UTC 2023 , Edited by admin on Fri Dec 15 15:06:08 UTC 2023
PRIMARY
ChEMBL
CHEMBL1068
Created by admin on Fri Dec 15 15:06:08 UTC 2023 , Edited by admin on Fri Dec 15 15:06:08 UTC 2023
PRIMARY
NCI_THESAURUS
C47643
Created by admin on Fri Dec 15 15:06:08 UTC 2023 , Edited by admin on Fri Dec 15 15:06:08 UTC 2023
PRIMARY
Related Record Type Details
Structure of OXCARBAZEPINE
BASIS OF STRENGTH->SUBSTANCE
ASSAY (HPLC)
USP
CYTOCHROME P450 2C19
METABOLIC ENZYME -> INHIBITOR
Ki
CYTOCHROME P450 3A5
METABOLIC ENZYME -> INDUCER
CHROMATOGRAPHIC PURITY (HPLC/UV)
Ki
Structure of OXCARBAZEPINE
EXCRETED UNCHANGED
AMOUNT EXCRETED
URINE
PLASMA PROTEIN FRACTION (HUMAN)
BINDER->LIGAND
BINDING
Structure of OXCARBAZEPINE
BASIS OF STRENGTH->SUBSTANCE
ASSAY (HPLC)
EP
CYTOCHROME P450 3A4
METABOLIC ENZYME -> INDUCER
Ki
Related Record Type Details
Structure of OXCARBAZEPINE ALCOHOL SULFATE
METABOLITE -> PARENT
Structure of LICARBAZEPINE GLUCURONIDE, (R)-
METABOLITE -> PARENT
Structure of LICARBAZEPINE
METABOLITE ACTIVE -> PRODRUG
Structure of 10,11-DIHYDROXY-10,11-DIHYDROCARBAZEPINE, TRANS-
METABOLITE -> PARENT
Structure of LICARBAZEPINE, (R)-
METABOLITE -> PARENT
Structure of 10,11-DIHYDROXY-10,11-DIHYDROCARBAZEPINE, CIS-
METABOLITE -> PARENT
Structure of .BETA.-D-GLUCOPYRANOSIDURONIC ACID, 5-(AMINOCARBONYL)-10,11-DIHYDRO-5H-DIBENZ(B,F)AZEPIN-10-YL
METABOLITE -> PARENT
Structure of ESLICARBAZEPINE GLUCURONIDE
METABOLITE -> PARENT
Related Record Type Details
Structure of 10-METHOXYIMINOSTILBENE
IMPURITY -> PARENT
UNSPECIFIED
EP
Structure of DE(5-CARBOXAMIDE)OXCARBAZEPINE
IMPURITY -> PARENT
UNSPECIFIED
EP
Structure of N-FORMYL OXCARBAZEPINE
IMPURITY -> PARENT
sum of impurities K and L: maximum 0.1 per cent
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of 5-ETHYL-10-METHOXY DIBENZAZEPINE
IMPURITY -> PARENT
UNSPECIFIED
EP
Structure of 1-(10-METHOXY-5H-DIBENZO(B,F)AZEPIN-5-YL)ETHANONE
IMPURITY -> PARENT
Structure of N-ACETYL OXCARBAZEPINE
IMPURITY -> PARENT
sum of impurities K and L: maximum 0.1 per cent
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of CARBAMAZEPINE
IMPURITY -> PARENT
UNSPECIFIED
EP
Structure of 10-METHOXYIMINOSTILBENE-5-CARBONYLCHLORIDE
IMPURITY -> PARENT
UNSPECIFIED
EP
Structure of DIBENZAZEPINE-10,11-DIONE
IMPURITY -> PARENT
UNSPECIFIED
EP
Structure of 10-(10-OXO-10,11-DIHYDRO-5H-DIBENZO(B,F)AZEPINE-5-CARBOXAMIDO)-5H-DIBENZO(B,F)AZEPINE-5-CARBOXAMIDE
IMPURITY -> PARENT
UNSPECIFIED
EP
Structure of 10-METHOXYCARBAMAZEPINE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of DIBENZAZEPINE
IMPURITY -> PARENT
UNSPECIFIED
EP
Structure of 11-KETO OXCARBAZEPINE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Related Record Type Details
Structure of LICARBAZEPINE
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Tmax PHARMACOKINETIC FASTED CONDITION

SINGLE DOSE ADMINISTRATION

HEALTHY MALE SUBJECTS

Volume of Distribution PHARMACOKINETIC
Structure of OXCARBAZEPINE
MHD
PHARMACOKINETIC
Biological Half-life PHARMACOKINETIC
Structure of OXCARBAZEPINE
MHD
PHARMACOKINETIC
Extended Release; Parent drug
PHARMACOKINETIC
Immediate release; Parent drug
PHARMACOKINETIC
MHD
PHARMACOKINETIC
Immediate release; MHD
PHARMACOKINETIC
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