TENOFOVIR ANHYDROUS

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C9H14N5O4P
Molecular Weight	287.2123
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of TENOFOVIR ANHYDROUS

Structure Search

SMILES

C[C@H](CN1C=NC2=C1N=CN=C2N)OCP(O)(O)=O

InChI

InChIKey=SGOIRFVFHAKUTI-ZCFIWIBFSA-N

InChI=1S/C9H14N5O4P/c1-6(18-5-19(15,16)17)2-14-4-13-7-8(10)11-3-12-9(7)14/h3-4,6H,2,5H2,1H3,(H2,10,11,12)(H2,15,16,17)/t6-/m1/s1

HIDE SMILES / InChI

Molecular Formula	C9H14N5O4P
Molecular Weight	287.2123
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:49:08 UTC 2023` Edited by `admin` on `Fri Dec 15 15:49:08 UTC 2023`
Record UNII	W4HFE001U5
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

TENOFOVIR ANHYDROUS

Common Name

English

tenofovir [INN]

Common Name

English

TENOFOVIR [MI]

Common Name

English

Tenofovir [WHO-DD]

Common Name

English

GS-1275

Code

English

PHOSPHONIC ACID, P-(((1R)-2-(6-AMINO-9H-PURIN-9-YL)-1-METHYLETHOXY)METHYL)-

Systematic Name

English

(R)-9-(2-PHOSPHONOMETHOXYPROPYL)ADENINE

Systematic Name

English

Classification Tree Code System Code

NDF-RT

N0000175459

Created by admin on Fri Dec 15 15:49:09 UTC 2023 , Edited by admin on Fri Dec 15 15:49:09 UTC 2023

NDF-RT

N0000175656

Created by admin on Fri Dec 15 15:49:09 UTC 2023 , Edited by admin on Fri Dec 15 15:49:09 UTC 2023

NDF-RT

N0000009947

Created by admin on Fri Dec 15 15:49:09 UTC 2023 , Edited by admin on Fri Dec 15 15:49:09 UTC 2023

NDF-RT

N0000175462

Created by admin on Fri Dec 15 15:49:09 UTC 2023 , Edited by admin on Fri Dec 15 15:49:09 UTC 2023

NDF-RT

N0000175459

Created by admin on Fri Dec 15 15:49:09 UTC 2023 , Edited by admin on Fri Dec 15 15:49:09 UTC 2023

NDF-RT

N0000175459

Created by admin on Fri Dec 15 15:49:09 UTC 2023 , Edited by admin on Fri Dec 15 15:49:09 UTC 2023

Code System Code Type Description

WIKIPEDIA

Microbicides for sexually transmitted diseases

Created by admin on Fri Dec 15 15:49:09 UTC 2023 , Edited by admin on Fri Dec 15 15:49:09 UTC 2023

PRIMARY

MERCK INDEX

m10559

Created by admin on Fri Dec 15 15:49:09 UTC 2023 , Edited by admin on Fri Dec 15 15:49:09 UTC 2023

PRIMARY

Merck Index

PUBCHEM

464205

Created by admin on Fri Dec 15 15:49:09 UTC 2023 , Edited by admin on Fri Dec 15 15:49:09 UTC 2023

PRIMARY

EPA CompTox

DTXSID9040132

Created by admin on Fri Dec 15 15:49:09 UTC 2023 , Edited by admin on Fri Dec 15 15:49:09 UTC 2023

PRIMARY

INN

7913

Created by admin on Fri Dec 15 15:49:09 UTC 2023 , Edited by admin on Fri Dec 15 15:49:09 UTC 2023

PRIMARY

SMS_ID

100000085232

Created by admin on Fri Dec 15 15:49:09 UTC 2023 , Edited by admin on Fri Dec 15 15:49:09 UTC 2023

PRIMARY

RXCUI

1546017

Created by admin on Fri Dec 15 15:49:09 UTC 2023 , Edited by admin on Fri Dec 15 15:49:09 UTC 2023

PRIMARY

RxNorm

EVMPD

SUB25192

Created by admin on Fri Dec 15 15:49:09 UTC 2023 , Edited by admin on Fri Dec 15 15:49:09 UTC 2023

ALTERNATIVE

NCI_THESAURUS

C170540

Created by admin on Fri Dec 15 15:49:09 UTC 2023 , Edited by admin on Fri Dec 15 15:49:09 UTC 2023

PRIMARY

FDA UNII

W4HFE001U5

Created by admin on Fri Dec 15 15:49:09 UTC 2023 , Edited by admin on Fri Dec 15 15:49:09 UTC 2023

PRIMARY

EVMPD

SUB04721MIG

Created by admin on Fri Dec 15 15:49:09 UTC 2023 , Edited by admin on Fri Dec 15 15:49:09 UTC 2023

PRIMARY

DRUG BANK

DB00300

Created by admin on Fri Dec 15 15:49:09 UTC 2023 , Edited by admin on Fri Dec 15 15:49:09 UTC 2023

PRIMARY

DAILYMED

W4HFE001U5

Created by admin on Fri Dec 15 15:49:09 UTC 2023 , Edited by admin on Fri Dec 15 15:49:09 UTC 2023

PRIMARY

CAS

147127-20-6

Created by admin on Fri Dec 15 15:49:09 UTC 2023 , Edited by admin on Fri Dec 15 15:49:09 UTC 2023

PRIMARY

Related Record Type Details


					I81U7H57XI

OAT-1

TRANSPORTER -> SUBSTRATE

Comments:

May cause renal toxicity

Amount:


					99YXE507IL

TENOFOVIR

SALT/SOLVATE -> PARENT

Amount:


					BQG94QJ69I

ABCC-4

TRANSPORTER -> SUBSTRATE

Amount:


					99YXE507IL

TENOFOVIR

SOLVATE->ANHYDROUS

Amount:


					ZWJ2Y6JZWY

OAT-3

TRANSPORTER -> SUBSTRATE

Amount:


					859A956UY8

HUMAN IMMUNODEFICIENCY VIRUS TYPE 1

TARGET ORGANISM->INHIBITOR

Qualification:

EC50

Amount:


					A3Z87NSO0U

HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 POLYMERASE

TARGET -> INHIBITOR

Amount:

Related Record Type Details


					F4YU4LON7I

TENOFOVIR DISOPROXIL

PRODRUG -> METABOLITE ACTIVE

Amount:


					TL2NJ3X9HC

TENOFOVIR DIPHOSPHATE

METABOLITE ACTIVE -> PARENT

Amount:


					SGK6176ZDO

TENOFOVIR AMIBUFENAMIDE

PRODRUG -> METABOLITE ACTIVE

Amount:


					K7J545MEMA

TENOFOVIR EXALIDEX

PRODRUG -> METABOLITE ACTIVE

Amount:


					EL9943AG5J

TENOFOVIR ALAFENAMIDE

PRODRUG -> METABOLITE ACTIVE

Amount:


					S53822VS43

PRODRUG -> METABOLITE ACTIVE

Comments:

Activated in liver cells.

Amount:

Related Record Type Details


					OTT9J7900I

TENOFOVIR DISOPROXIL FUMARATE

PARENT -> IMPURITY

Amount:

Related Record Type Details


					W4HFE001U5

TENOFOVIR ANHYDROUS

ACTIVE MOIETY

Amount: