U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ABSOLUTE
Molecular Formula C22H27F3O4S
Molecular Weight 444.508
Optical Activity UNSPECIFIED
Defined Stereocenters 9 / 9
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of FLUTICASONE

SMILES

[H][C@@]12C[C@@H](C)[C@](O)(C(=O)SCF)[C@@]1(C)C[C@H](O)[C@@]3(F)[C@@]2([H])C[C@H](F)C4=CC(=O)C=C[C@]34C

InChI

InChIKey=MGNNYOODZCAHBA-GQKYHHCASA-N
InChI=1S/C22H27F3O4S/c1-11-6-13-14-8-16(24)15-7-12(26)4-5-19(15,2)21(14,25)17(27)9-20(13,3)22(11,29)18(28)30-10-23/h4-5,7,11,13-14,16-17,27,29H,6,8-10H2,1-3H3/t11-,13+,14+,16+,17+,19+,20+,21+,22+/m1/s1

HIDE SMILES / InChI
Molecular Formula C22H27F3O4S
Molecular Weight 444.508
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 9 / 9
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

Unknown
86413
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:49:06 UTC 2023
Edited
by admin
on Fri Dec 15 15:49:06 UTC 2023
Record UNII
CUT2W21N7U
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
FLUTICASONE
HSDB   INN   MART.   VANDF   WHO-DD  
INN  
Official Name English
FLUTICAPS
Brand Name English
FLUTICASONE [MART.]
Common Name English
Fluticasone [WHO-DD]
Common Name English
OPTINOSE
Common Name English
S-(FLUOROMETHYL) (6.ALPHA.,11.BETA.,16.ALPHA.,17.ALPHA.)-6,9-DIFLUORO-11,17-DIHYDROXY-16-METHYL-3-OXOANDROSTA-1,4-DIENE-17-CARBOTHIOATE
Common Name English
FLUTICASONE [VANDF]
Common Name English
fluticasone [INN]
Common Name English
OPN-375
Code English
R01AD08
Code English
FLUTICASONE [HSDB]
Common Name English
Classification Tree Code System Code
WHO-ATC R03AK11
Created by admin on Fri Dec 15 15:49:07 UTC 2023 , Edited by admin on Fri Dec 15 15:49:07 UTC 2023
WHO-ATC D07AC17
Created by admin on Fri Dec 15 15:49:07 UTC 2023 , Edited by admin on Fri Dec 15 15:49:07 UTC 2023
NDF-RT N0000175576
Created by admin on Fri Dec 15 15:49:07 UTC 2023 , Edited by admin on Fri Dec 15 15:49:07 UTC 2023
NCI_THESAURUS C521
Created by admin on Fri Dec 15 15:49:07 UTC 2023 , Edited by admin on Fri Dec 15 15:49:07 UTC 2023
WHO-ATC R03AK06
Created by admin on Fri Dec 15 15:49:07 UTC 2023 , Edited by admin on Fri Dec 15 15:49:07 UTC 2023
WHO-ATC R01AD58
Created by admin on Fri Dec 15 15:49:07 UTC 2023 , Edited by admin on Fri Dec 15 15:49:07 UTC 2023
WHO-ATC R01AD08
Created by admin on Fri Dec 15 15:49:07 UTC 2023 , Edited by admin on Fri Dec 15 15:49:07 UTC 2023
NDF-RT N0000175450
Created by admin on Fri Dec 15 15:49:07 UTC 2023 , Edited by admin on Fri Dec 15 15:49:07 UTC 2023
WHO-VATC QR03AK06
Created by admin on Fri Dec 15 15:49:07 UTC 2023 , Edited by admin on Fri Dec 15 15:49:07 UTC 2023
WHO-ATC R03BA05
Created by admin on Fri Dec 15 15:49:07 UTC 2023 , Edited by admin on Fri Dec 15 15:49:07 UTC 2023
WHO-VATC QD07AC17
Created by admin on Fri Dec 15 15:49:07 UTC 2023 , Edited by admin on Fri Dec 15 15:49:07 UTC 2023
WHO-VATC QR03BA05
Created by admin on Fri Dec 15 15:49:07 UTC 2023 , Edited by admin on Fri Dec 15 15:49:07 UTC 2023
WHO-ATC R03AK10
Created by admin on Fri Dec 15 15:49:07 UTC 2023 , Edited by admin on Fri Dec 15 15:49:07 UTC 2023
WHO-VATC QR03AK11
Created by admin on Fri Dec 15 15:49:07 UTC 2023 , Edited by admin on Fri Dec 15 15:49:07 UTC 2023
WHO-VATC QR01AD08
Created by admin on Fri Dec 15 15:49:07 UTC 2023 , Edited by admin on Fri Dec 15 15:49:07 UTC 2023
WHO-VATC QR01AD58
Created by admin on Fri Dec 15 15:49:07 UTC 2023 , Edited by admin on Fri Dec 15 15:49:07 UTC 2023
Code System Code Type Description
CAS
90566-53-3
Created by admin on Fri Dec 15 15:49:07 UTC 2023 , Edited by admin on Fri Dec 15 15:49:07 UTC 2023
PRIMARY
HSDB
7740
Created by admin on Fri Dec 15 15:49:07 UTC 2023 , Edited by admin on Fri Dec 15 15:49:07 UTC 2023
PRIMARY
IUPHAR
6699
Created by admin on Fri Dec 15 15:49:07 UTC 2023 , Edited by admin on Fri Dec 15 15:49:07 UTC 2023
PRIMARY
WIKIPEDIA
FLUTICASONE
Created by admin on Fri Dec 15 15:49:07 UTC 2023 , Edited by admin on Fri Dec 15 15:49:07 UTC 2023
PRIMARY
PUBCHEM
5311101
Created by admin on Fri Dec 15 15:49:07 UTC 2023 , Edited by admin on Fri Dec 15 15:49:07 UTC 2023
PRIMARY
INN
5636
Created by admin on Fri Dec 15 15:49:07 UTC 2023 , Edited by admin on Fri Dec 15 15:49:07 UTC 2023
PRIMARY
SMS_ID
100000080975
Created by admin on Fri Dec 15 15:49:07 UTC 2023 , Edited by admin on Fri Dec 15 15:49:07 UTC 2023
PRIMARY
LACTMED
Fluticasone, Topical
Created by admin on Fri Dec 15 15:49:07 UTC 2023 , Edited by admin on Fri Dec 15 15:49:07 UTC 2023
PRIMARY
EVMPD
SUB07760MIG
Created by admin on Fri Dec 15 15:49:07 UTC 2023 , Edited by admin on Fri Dec 15 15:49:07 UTC 2023
PRIMARY
LACTMED
Fluticasone, Inhaled
Created by admin on Fri Dec 15 15:49:07 UTC 2023 , Edited by admin on Fri Dec 15 15:49:07 UTC 2023
PRIMARY
FDA UNII
CUT2W21N7U
Created by admin on Fri Dec 15 15:49:07 UTC 2023 , Edited by admin on Fri Dec 15 15:49:07 UTC 2023
PRIMARY
CHEBI
5134
Created by admin on Fri Dec 15 15:49:07 UTC 2023 , Edited by admin on Fri Dec 15 15:49:07 UTC 2023
PRIMARY
DAILYMED
CUT2W21N7U
Created by admin on Fri Dec 15 15:49:07 UTC 2023 , Edited by admin on Fri Dec 15 15:49:07 UTC 2023
PRIMARY
EPA CompTox
DTXSID0044022
Created by admin on Fri Dec 15 15:49:07 UTC 2023 , Edited by admin on Fri Dec 15 15:49:07 UTC 2023
PRIMARY
DRUG BANK
DB13867
Created by admin on Fri Dec 15 15:49:07 UTC 2023 , Edited by admin on Fri Dec 15 15:49:07 UTC 2023
PRIMARY
NCI_THESAURUS
C61767
Created by admin on Fri Dec 15 15:49:07 UTC 2023 , Edited by admin on Fri Dec 15 15:49:07 UTC 2023
PRIMARY
MESH
C065382
Created by admin on Fri Dec 15 15:49:07 UTC 2023 , Edited by admin on Fri Dec 15 15:49:07 UTC 2023
PRIMARY
ChEMBL
CHEMBL1473
Created by admin on Fri Dec 15 15:49:07 UTC 2023 , Edited by admin on Fri Dec 15 15:49:07 UTC 2023
PRIMARY
RXCUI
41126
Created by admin on Fri Dec 15 15:49:07 UTC 2023 , Edited by admin on Fri Dec 15 15:49:07 UTC 2023
PRIMARY RxNorm
Related Record Type Details
Structure of FLUTICASONE FUROATE
DERIVATIVE -> PARENT
PLASMA PROTEIN FRACTION (HUMAN)
BINDER->LIGAND
BINDING
Structure of FLUTICASONE PROPIONATE
DERIVATIVE -> PARENT
Related Record Type Details
Structure of 6.ALPHA.,9.ALPHA.-DIFLUORO-11.BETA.,17.ALPHA.-DIHYDROXY-16.ALPHA.-METHYL-3-OXOANDROSTA-1,4-DIENE-17.BETA.-CARBOTHIOIC ACID
IMPURITY -> PARENT
Related Record Type Details
Structure of FLUTICASONE
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Biological Half-life PHARMACOKINETIC
Volume of Distribution PHARMACOKINETIC
NIH
NCATS
PRIVACY ACT
ACCESSIBILITY
DISCLAIMER
HHS VULNERABILITY DISCLOSURE
For language access assistance, contact the NCATS Public Information Officer
National Center for Advancing Translational Sciences (NCATS),
6701 Democracy Boulevard, Bethesda MD 20892-4874 • 301-594-8966